Search Results - pharmaceuticals

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New Drugs for Treatment of Type 1 Diabetes
Technology Description Oregon State University is seeking a licensee to develop and commercialize a new family of compounds that target the Ah receptor for treatment of Type 1 Diabetes. The compounds are based on the parental compound 11-Cl-BBQ, the use of which is described PCT patent application No. US2015/057873, in U.S. patent No. 10,308,649, and...
Published: 6/23/2020   |   Inventor(s): Jit Chakravarty, Nancy Kerkvliet, Siva Kolluri, Sebastian Bernales
Keywords(s): Diabetes, pharmaceuticals, Therapeutic, Type 1 Diabetes
Category(s): Therapeutics
Substituted Phenols and Benzenes for Pharmaceuticals, Agrochemicals and Synthetic Materials
Technology Description This technology licensing opportunity is for novel phenol and benzene compounds with any number of substituents and complete positional selectivity. Synthesis of the compounds is achieved by a new synthetic method. The method provides a one-step conversion of readily available starting materials to give phenols with complete...
Published: 5/20/2020   |   Inventor(s): Chris Beaudry, Xiaojie Zhang
Keywords(s): agrochemical, benzenes, chemistry, medicinal, organic, pharmaceuticals, phenols, polymer, substituted, synthesis
Category(s): Agricultural, Chemical, Therapeutics
Treatment for Hypertension
Technology Description This technology opportunity provides antisense oligomer compounds and methods for the treatment of hypertension that overcome the various limitations and drawbacks associated with the use of substrate inhibitors. The compounds accumulate in the kidney, which allows for efficient dosing, and can be developed for transdermal, subcutaneous,...
Published: 1/7/2020   |   Inventor(s): Patrick Iversen, Andrew Annalora
Keywords(s): Hypertension, pharmaceuticals, Transplantation
Category(s): Therapeutics
Mouse Model for Insulin Resistance
Opportunity Description Oregon State University is SEEKING RESEARCH COLLABORATIONS or LICENSEES for pharmaceutical R&D, or obesity and diabetes research, to exploit A NEW TYPE 2 DIABETES MOUSE MODEL. Created by Oregon State University professor Chrissa Kioussi, the mouse model is a SKELETAL MUSCLE SPECIFIC PITX2 NULL MOUSE. Development of the mouse...
Published: 2/22/2017   |   Inventor(s): Chrissa Kioussi
Keywords(s): Biotechnology, Diabetes, insulin resistance, pharmaceuticals, Type 2 Diabetes
Category(s): Biological Materials, Chemical, Medical Devices, Therapeutics
CTIP2 Diagnostic Marker for Head and Neck Cancer
Technology Description This technology opportunity provides a method for detecting CTIP2 or CTIP2L and for their use as biomarkers for squamous cell carcinoma. This technology can be used to develop kits for detecting SCC in a patient. The kit can include a CTIP2 and CTIP2L -specific antibody, oligonucleotides, or primers, and a chart or diagram showing...
Published: 5/31/2016   |   Inventor(s): Arup Indra, Mark Leid, Joseph Abecassis, Gitali Indra
Keywords(s): Biomedical, Diagnostic, pharmaceuticals, Research Tools
Category(s): Diagnostics
Biolamina Plate Bioreactor
Technology Description This technology includes bioreactor devices capable of converting organic species into fuels using microchannel technology combined with bio-lamina substrates modified with biologically active materials. The reactor is comprised of lamina each containing an encapsulated biofilm that carries out a desired conversion reaction. This...
Published: 5/20/2016   |   Inventor(s): Goran Jovanovic, Kate Schilke, Frederick Atadana, Chris Loeb
Keywords(s): Advanced Technology and Manufacturing Inst. (ATAMI), Agriculture, Biofuels, Biological & Environmental Engineering, Biomechanics, Biotechnology, Gas-to-Liquid Technology, pharmaceuticals, Process Intensification
Category(s): Chemical, Device, Engineering, Materials Science, Nanoscience & Microtechnologies, Sustainability & Cleantechnologies
New Antifungal Analogs
Technology Description This technology licensing opportunity provides biosynthetic methods for the production of the antidiabetic drug voglibose. Briefly, antifungal validamycin A analogs, including 1,1′-bis-valienamine, are produced using valN mutant strains of Streptomyces organisms, such as Streptomyces hygroscopicus. The 1,1′-bis-valienamine...
Published: 5/20/2016   |   Inventor(s): Taifo Mahmud, Hui Xu, Jongtae Yang, Zixin Deng, Linquan Bai
Keywords(s): Agriculture, Biomedical, Drug, drugs, Medical Science & Technologies, pharmaceuticals
Category(s): Therapeutics, Agricultural
Antiproliferative Peptide Coibamide A
Technology Description Researchers at Oregon State University have discovered, isolated, and purified a new antiproliferative compound, Coibamide A, which provides for a new and potent family of antiproliferative compounds. The peptidic molecular structure of Coibamide A presents a large number of possible combinations and permutations of component...
Published: 5/19/2016   |   Inventor(s): Kerry Mcphail, Rebecca Medina, William Gerwick, Douglas Goeger, Susan Moobery, Todd Capson
Keywords(s): Biomedical, Biotechnology, Medical Science & Technologies, pharmaceuticals
Category(s): Therapeutics
Low Cost Methods for Producing Microchannel Process Technology
Technology Description This manufacturing architecture uses microchannel flow inserts to eliminate the need for small photochemically-machined features, thereby enabling the use of stamping and, in turn, improving the material utilization and reducing the cost of compact, microchannel heat exchangers made from refractory alloys needed for high-temperature...
Published: 5/17/2016   |   Inventor(s): Brian Paul, Samuel Brannon
Keywords(s): Advanced Technology and Manufacturing Inst. (ATAMI), Chemical Synthesis, Chemicals / Chemical Engineering, Electrical & Computer Engineering, Energy Storage, Heat exchangers, Heat Transfer, Manufacturing, Mechanical & Areospace Engineering, Metal Alloy, Microchannel, Mixing, Nanotechnology, pharmaceuticals, Physical Science, Physics / Applied Engineering, Process/Procedure, Reactor, Research Tools
Category(s): Device, Engineering, Medical Devices, Nanoscience & Microtechnologies, Physical Science, Research Tools, Sustainability & Cleantechnologies, Transportation
Inhibitors of Transporters or Uptake of Monoaminergic Neurotransmitters
Technology Description This technology is a simple and efficient way for synthesizing Synosutine, a drug to be potentially used to treat depression and neuropathic pain.Features & Benefits Much more efficient and quicker synthesis pathway than that for CymbaltaMore balanced inhibition of serotonin and norepinephrine transporters makes Synosutine...
Published: 5/16/2016   |   Inventor(s): James White, David Chan, David Wong, Rajan Juniku, Jongtae Yang
Keywords(s): Biomedical, pharmaceuticals
Category(s): Chemistry
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