Search Results - biomedical

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Biosynthetic Gene Cluster for the Peptide Antibiotic Enduracidin
Technology Description To produce a library of S. fungicidicus mutants, an in vitro transposon-based method was devised to randomly insert a selectable marker and oriT element in fosmid inserts carrying segments of the enramycin biosynthetic gene cluster and adjacent regions. This library of mutagenized fosmids was screened to identify specific disrupted...
Published: 3/13/2024   |   Inventor(s): T. Zabriskie, Xihou 希厚 Yin 银
Keywords(s): Biomedical, Biotechnology, Medical Science & Technologies, pharmaceuticals
Category(s): Therapeutics
Microfluidic device for blood plasma separation and assays
Technology Description Oregon State University is seeking a licensee for a microfluidic device that separates blood plasma from whole blood and can facilitate downstream assays. The device can be used with raw blood or blood treated with anticoagulants, both with a lower volume than is required by current testing strategies. Testing zones of different...
Published: 1/16/2023   |   Inventor(s): Gayan Bandara, Matthew Kremer, Vincent Remcho
Keywords(s): Biomedical, Blood, Blood coagulation chemistry, Membrane, Polycaprolactone, surface chemistry, Wicking microfluidics
Category(s): Device, Diagnostics, Information Technology, Nanoscience & Microtechnologies, Research Tools
Engineering Mechanisms to Connect One Muscle to Multiple Tendons in Surgery
Technology Description This technology is a new tendon-transfer surgical procedure that uses an implanted passive engineering mechanism for attaching multiple tendons to a single donor muscle. This improves hand function in physical interaction tasks such as grasping over the conventional method of directly suturing multiple tendons to a single muscle.Features...
Published: 1/7/2022   |   Inventor(s): Ravi Balasubramanian, Taymaz Homayouni
Keywords(s): Biomedical, Materials Science, Medical Science & Technologies, Veterinary Science & Technologies
Category(s): Medical Devices, Engineering, Device, Therapeutics
Fluidic devices with photo-actuated gates and re-patternable channels
Technology Description This patented technology (US 8,580,161) describes ways of controlling fluid movement in microfluidic devices and microwell plates. Fluid movement is achieved by controlling gating, valving, and permeation using light-actuated compounds such as a spiropyran. Prototypes have been tested in the lab and we are looking for a licensee...
Published: 5/10/2021   |   Inventor(s): Vincent Remcho, Jintana Nammoonnoy, Myra Koesdjojo
Keywords(s): Advanced Technology and Manufacturing Inst. (ATAMI), Biological & Environmental Engineering, Biomedical, Biotechnology, Chemicals / Chemical Engineering, Diagnostic, Medical Science & Technologies, Multiplexing, Nanotechnology, Physics / Applied Engineering, Research Tools
Category(s): Device, Chemical, Chemistry, Diagnostics, Engineering, Nanoscience & Microtechnologies, Research Tools
Fiducial Marker for CT and MRI
Technology Description Attachable fiducial marker with optimized contrast medium that provides optimal imaging in CT and MRI. The marker is easily attached to body of a patient and features proven dual imaging capability that simplifies workflow to save time and money. The triangular design with single side crimp provides for fast and accurate linking...
Published: 1/16/2023   |   Inventor(s): Sarah Nemanic, Jesse Terry, Milan Milovancev, Josiah Moses
Keywords(s): Biomedical
Category(s): Diagnostics
Antiproliferative Peptide Coibamide A
Technology Description Researchers at Oregon State University have discovered, isolated, and purified a new antiproliferative compound, Coibamide A, which provides for a new and potent family of antiproliferative compounds. The peptidic molecular structure of Coibamide A presents a large number of possible combinations and permutations of component...
Published: 5/10/2021   |   Inventor(s): Kerry Mcphail, Rebecca Medina, William Gerwick, Douglas Goeger, Susan Moobery, Todd Capson
Keywords(s): Biomedical, Biotechnology, Medical Science & Technologies, pharmaceuticals
Category(s): Therapeutics
Inhibitors of Transporters or Uptake of Monoaminergic Neurotransmitters
Technology Description This technology is a simple and efficient way for synthesizing Synosutine, a drug to be potentially used to treat depression and neuropathic pain.Features & Benefits Much more efficient and quicker synthesis pathway than that for CymbaltaMore balanced inhibition of serotonin and norepinephrine transporters makes Synosutine...
Published: 2/8/2024   |   Inventor(s): James White, David Chan, David Wong, Rajan Juniku, Jongtae Yang
Keywords(s): Biomedical, pharmaceuticals
Category(s): Chemistry
Genetic incorporation of tetrazine amino acids and use in bioorthogonal ligations
Technology Description Ideal bioorthogonal reactions containing high reaction rates, high selectivity and high stability would allow for stoichiometric labeling of biomolecules in minutes and eliminate the need to washout excess labeling reagent. Currently no general method exists for controlled stoichiometric or sub-stoichiometric labeling of proteins...
Published: 3/19/2024   |   Inventor(s): Ryan Mehl, Robert Blizzard
Keywords(s): Biological & Environmental Engineering, Biomedical, Biotechnology, Diagnostic, Labels, Protein Polymer Hybrids, Research Tools
Category(s): Diagnostics
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