Search Results - biomedical

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Inhibitors of Transporters or Uptake of Monoaminergic Neurotransmitters

Background One form of medical treatment for depression and neuropathic pain features a dual inhibitor called Cymbalta. This drug is manufactured and marketed by Eli Lilly. Researchers at Oregon State University have discovered a very efficient way of synthesizing Synosutine, which is comparable to Cymbalta in limited in vitro and in vivo assay....

Published: 6/17/2024 | Inventor(s): James White, David Chan, David Wong, Rajan Juniku, Jongtae Yang

Keywords(s): Biomedical, pharmaceuticals

Category(s): Chemistry

Biosynthetic Gene Cluster for the Peptide Antibiotic Enduracidin

Background The emerging and persistent threat of multidrug-resistant bacterial infections has resulted in enormous healthcare costs and poses major challenges to public health. To address the need for new antibiotics capable of combating the gowning problem of resistance, Oregon State University researchers cloned and patented the biosynthetic gene...

Published: 9/12/2024 | Inventor(s): T. Zabriskie, Xihou 希厚 Yin 银

Keywords(s): Biomedical, Biotechnology, Medical Science & Technologies, pharmaceuticals

Category(s): Therapeutics

Microfluidic device for blood plasma separation and assays

Technology Description Oregon State University is seeking a licensee for a microfluidic device that separates blood plasma from whole blood and can facilitate downstream assays. The device can be used with raw blood or blood treated with anticoagulants, both with a lower volume than is required by current testing strategies. Testing zones of different...

Published: 1/16/2023 | Inventor(s): Gayan Bandara, Matthew Kremer, Vincent Remcho

Keywords(s): Biomedical, Blood, Blood coagulation chemistry, Membrane, Polycaprolactone, surface chemistry, Wicking microfluidics

Category(s): Device, Diagnostics, Information Technology, Nanoscience & Microtechnologies, Research Tools

Engineering Mechanisms to Connect One Muscle to Multiple Tendons in Surgery

Technology Description This technology is a new tendon-transfer surgical procedure that uses an implanted passive engineering mechanism for attaching multiple tendons to a single donor muscle. This improves hand function in physical interaction tasks such as grasping over the conventional method of directly suturing multiple tendons to a single muscle.Features...

Published: 7/30/2024 | Inventor(s): Ravi Balasubramanian, Taymaz Homayouni

Keywords(s): Biomedical, Materials Science, Medical Science & Technologies, Veterinary Science & Technologies

Category(s): Medical Devices, Engineering, Device, Therapeutics

Fluidic devices with photo-actuated gates and re-patternable channels

Background Microfluidic devices are a popular means of analyzing minute quantities of samples and feature high-throughput sampling capabilities and suitability for providing highly controlled microreactor environments; however, many types of microfluidic devices and related fabrication approaches can be costly and require great effort and time to...

Published: 6/17/2024 | Inventor(s): Vincent Remcho, Jintana Nammoonnoy, Myra Koesdjojo

Keywords(s): Advanced Technology and Manufacturing Inst. (ATAMI), Biological & Environmental Engineering, Biomedical, Biotechnology, Chemicals / Chemical Engineering, Diagnostic, Medical Science & Technologies, Multiplexing, Nanotechnology, Physics / Applied Engineering, Research Tools

Category(s): Device, Chemical, Chemistry, Diagnostics, Engineering, Nanoscience & Microtechnologies, Research Tools

Fiducial Marker for CT and MRI

Technology Description Attachable fiducial marker with optimized contrast medium that provides optimal imaging in CT and MRI. The marker is easily attached to body of a patient and features proven dual imaging capability that simplifies workflow to save time and money. The triangular design with single side crimp provides for fast and accurate linking...

Published: 1/16/2023 | Inventor(s): Sarah Nemanic, Jesse Terry, Milan Milovancev, Josiah Moses

Keywords(s): Biomedical

Category(s): Diagnostics

Antiproliferative Peptide Coibamide A

Background Cancer is one of the leading causes of morbidity and mortality worldwide, and the number of cases is expected to rise to 22 million over the next 2 decades. Modified natural products continue to be an important source for new drugs that address unmet needs in the battle against cancer. Technology Description Researchers at Oregon...

Published: 6/17/2024 | Inventor(s): Kerry Mcphail, Rebecca Medina, William Gerwick, Douglas Goeger, Susan Moobery, Todd Capson

Keywords(s): Biomedical, Biotechnology, Medical Science & Technologies, pharmaceuticals

Category(s): Therapeutics

Genetic incorporation of tetrazine amino acids and use in bioorthogonal ligations

Technology Description Ideal bioorthogonal reactions containing high reaction rates, high selectivity and high stability would allow for stoichiometric labeling of biomolecules in minutes and eliminate the need to washout excess labeling reagent. Currently no general method exists for controlled stoichiometric or sub-stoichiometric labeling of proteins...

Published: 6/18/2024 | Inventor(s): Ryan Mehl, Robert Blizzard

Keywords(s): Biological & Environmental Engineering, Biomedical, Biotechnology, Diagnostic, Labels, Protein Polymer Hybrids, Research Tools

Category(s): Diagnostics