Search Results - therapeutic

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Antisense Agents for Treating SARS-CoV-2 Infection

Background In December 2019, cases of an acute respiratory disease were reported from Wuhan, the capital of Hubei province in China. The number of infections increased rapidly and spread to other areas of China and on January 13th, 2020, the first case was reported outside of China. The causative agent was identified as a novel coronavirus (CoV)...

Published: 7/31/2023 | Inventor(s): David Stein, Hong Moulton, Kyle Rosenke, Heinrich Feldmann

Keywords(s): antisense, coronavirus, covid-19, Drug, SARS-CoV-2, Therapeutic

Category(s): Therapeutics

New Drugs for Treatment of Type 1 Diabetes

Background Type 1 diabetes (T1D) is a life-threatening autoimmune disease that usually appears in childhood without warning. Current treatment options involve the administration of various insulin analogs and auxiliary therapies. The global market for T1D treatment is over $25 billion and growing. T1D is caused by the immune-mediated destruction...

Published: 6/10/2024 | Inventor(s): Siva Kolluri, Nancy Kerkvliet, Jit Chakravarty, Sebastian Bernales

Keywords(s): Diabetes, pharmaceuticals, Therapeutic, Type 1 Diabetes

Category(s): Therapeutics

Peptide Inhibitors of Gonorrhoeae

Technology Description Antigonococcal peptide inhibitors of Neisseria gonorrhoeae that act against a non-conventional new target, nitrite reductase AniA, that is necessary for N. gonorrhoeae anaerobic respiration and biofilm formation. The anaerobic life style is an important state during disease and favored in biofilms, which form in cervical gonococcal...

Published: 12/23/2021 | Inventor(s): Aleksandra Sikora, Konstantin Korotkov

Keywords(s): Antibiotics, Antimicrobial, Drug, Drug Development, Gonorrhea, Inhibitor, Microbiology, Peptide, Therapeutic

Category(s): Therapeutics, Vaccines

New Approach for Treatment of Type I Diabetes

Technology Description This licensing and collaborative research opportunity relates to a new approach to treating diabetes mellitus type 1 (T1DM). The patent pending methods of treatment focus on the use of compounds that provide suppression of autoimmune responses that lead to destruction of pancreatic beta cells. The possibility of preventing disease...

Published: 5/24/2023 | Inventor(s): Nancy Kerkvliet, Siva Kolluri

Keywords(s): Diabetes, Drug, Immune, Therapeutic

Category(s): Chemical, Therapeutics

Lymphatic drug delivery system and drugs for metastatic melanoma

Technology Description Oregon State University is seeking a licensee for a patented drug delivery system for the treatment of metastatic melanoma. The system is composed of biodegradable, biocompatible, and stable nanoparticles built from amphiphilic block copolymers and contains a mix of drugs commonly used to treat cancer, all while being nontoxic...

Published: 1/16/2023 | Inventor(s): Adam Alani

Keywords(s): Cancer, Drug, Drug Delivery, drugs, lymphatic, melanoma, metastatic tumor, pharmaceuticals, Therapeutic

Category(s): Therapeutics