Search Results - antibiotics

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Technology Description Antigonococcal peptide inhibitors of Neisseria gonorrhoeae that act against a non-conventional new target, nitrite reductase AniA, that is necessary for N. gonorrhoeae anaerobic respiration and biofilm formation. The anaerobic life style is an important state during disease and favored in biofilms, which form in cervical gonococcal...

Published: 12/23/2021 | Inventor(s): Aleksandra Sikora, Konstantin Korotkov

Keywords(s): Antibiotics, Antimicrobial, Drug, Drug Development, Gonorrhea, Inhibitor, Microbiology, Peptide, Therapeutic

Category(s): Therapeutics, Vaccines

Pactamycin Analogs Having Antibacterial, Antitumor, and Antimalarial Activity

Background The global emergence of multi-drug resistant bacterial infections has resulted in enormous costs and has become a major threat to public health. About seventy percent of nosocomial infections are resistant to at least one commonly use antibiotic. Pactamycin is a structurally unique aminocyclitol antibiotic isolated from Streptomyces pactum....

Published: 6/17/2024 | Inventor(s): Taifo Mahmud, Takuya Ito, Niran Roongsawang, Norifumi Shirasaka, Patricia Flatt

Keywords(s): Antibiotics, antiviral, Cancer, Malaria

Category(s): Therapeutics