Search Results - cancer

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Anti-cancer Compounds

Technology Description This technology describes using compounds to induce cell death in Bcl-2 high-expressing cancer cells refractory to chemotherapeutic drugs but with minimal effects on normal cells. Further, the anti-cancer effect of these compounds is also confirmed in mouse xenograft studies. These results indicate that our compounds are effective...

Published: 1/7/2022 | Inventor(s): Siva Kolluri, Prasad Kopparapu

Keywords(s): Cancer, metastatic tumor, small peptides

Category(s): Biological Materials, Chemical, Diagnostics, Research Tools, Therapeutics

A Method to Treat Alzheimer’s, Heart and Liver Diseases

Technology Description This technology describes a process for the preparation of the tripeptide glutathione or its precursors to be delivered to the mitochondria for treating age-related conditions, toxicologic exposures, neurodegeneration, heart disease, and liver damage. More specifically, glutathione precursors and derivatives are coupled to a lipophilic...

Published: 5/26/2021 | Inventor(s): Tory Hagen, Joseph Beckman, Pamela Beilby

Keywords(s): ALS, Alzheimer's, Antioxidant, Cancer, Liver disease, Medical Science & Technologies, Mitochondria, Neurodegenerative disease

Category(s): Biological Materials, Chemical, Diagnostics, Research Tools, Therapeutics

Pactamycin Analogs Having Antibacterial, Antitumor, and Antimalarial Activity

Background The global emergence of multi-drug resistant bacterial infections has resulted in enormous costs and has become a major threat to public health. About seventy percent of nosocomial infections are resistant to at least one commonly use antibiotic. Pactamycin is a structurally unique aminocyclitol antibiotic isolated from Streptomyces pactum....

Published: 6/17/2024 | Inventor(s): Taifo Mahmud, Takuya Ito, Niran Roongsawang, Norifumi Shirasaka, Patricia Flatt

Keywords(s): Antibiotics, antiviral, Cancer, Malaria

Category(s): Therapeutics

Lymphatic drug delivery system and drugs for metastatic melanoma

Technology Description Oregon State University is seeking a licensee for a patented drug delivery system for the treatment of metastatic melanoma. The system is composed of biodegradable, biocompatible, and stable nanoparticles built from amphiphilic block copolymers and contains a mix of drugs commonly used to treat cancer, all while being nontoxic...

Published: 1/16/2023 | Inventor(s): Adam Alani

Keywords(s): Cancer, Drug, Drug Delivery, drugs, lymphatic, melanoma, metastatic tumor, pharmaceuticals, Therapeutic

Category(s): Therapeutics