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Mouse Model for Vitamin D Regulated
Antimicrobial
Peptide Expression
Technology Description Oregon State University is seeking collaborative research opportunities or licensees for a humanized mouse model for vitamin D regulated
antimicrobial
peptide expression. The developed animal model is a transgenic mouse that carries a 6.2 kb human genomic DNA that possess the cathelicidin antimicrobial peptide (CAMP) gene. Vitamin...
Published: 1/16/2023
|
Inventor(s):
Adrian Gombart
Keywords(s):
Animal Model
,
Antimicrobial
,
Biotechnology
,
Vitamin D regulation
Category(s):
Therapeutics
,
Biological Materials
,
Research Tools
Peptide Inhibitors of Gonorrhoeae
Technology Description Antigonococcal peptide inhibitors of Neisseria gonorrhoeae that act against a non-conventional new target, nitrite reductase AniA, that is necessary for N. gonorrhoeae anaerobic respiration and biofilm formation. The anaerobic life style is an important state during disease and favored in biofilms, which form in cervical gonococcal...
Published: 12/23/2021
|
Inventor(s):
Aleksandra Sikora
,
Konstantin Korotkov
Keywords(s):
Antibiotics
,
Antimicrobial
,
Drug
,
Drug Development
,
Gonorrhea
,
Inhibitor
,
Microbiology
,
Peptide
,
Therapeutic
Category(s):
Therapeutics
,
Vaccines
Antimicrobial
Surface Coating
Background of Invention Advances in biomaterials engineering have led to numerous successful technologies in the medical field and have improved the quality of life for millions of people. However, there are still problems with blood coagulation, fibrosis, and infections associated with currently available materials. Most materials used in medical...
Published: 6/17/2024
|
Inventor(s):
Joseph Mcguire
,
Pranav Joshi
Keywords(s):
Advanced Technology and Manufacturing Inst. (ATAMI)
,
Antimicrobial
,
Peptide
,
polymer
Category(s):
Engineering
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