Search Results - Biological+Materials

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Meadowfoam derived sunscreen compounds that reduce UVB-induced DNA damage Background Chronic skin exposure to solar ultraviolet radiation (UVR) leads to accumulated DNA damage resulting in skin aging and the possibility of cancer. To prevent this, sunscreens are formulated with additives that reflect or absorb UV wavelengths that are incident on...

Published: 2/26/2024 | Inventor(s): Gitali Indra, Jan Frederik Stevens, Arup Indra, Evan Carpenter

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Category(s): Biological Materials, Chemical

Improved Lox SItes for Cre Recombination Plants

Provides recombination sites for the most widely used recombinase that facilitate increased plant activity Background Site-specific recombinases are widely used molecular tools for performing DNA manipulations both in vitro and in vivo, with applications in research and biotechnology. This includes deletion, integration, and inversion of target...

Published: 1/4/2024 | Inventor(s): Greg Goralogia, Steven Strauss

Keywords(s): Recombinase

Category(s): Biological Materials, Agricultural

Multimeric Therapeutic Nanobodies

Background Assembling nanobodies (Nb) into polyvalent multimers is a powerful strategy for improving the effectiveness of Nb-based therapeutics and biotechnological tools. However, generally effective approaches to Nb assembly are currently restricted to the N- or C-termini, greatly limiting the diversity of Nb multimers that can be produced. Here,...

Published: 8/11/2023 | Inventor(s): Ryan Mehl, Elise Van Fossen, Riley Bednar

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Category(s): Nanoscience & Microtechnologies, Physical Science, Biological Materials

Molecular Probe and Sensor for Detecting Cu2+

Background The detection of trace quantities of copper in environmental and biological samples is in high demand. Numerous analytical techniques are available to detect trace quantities of Cu2+, including atomic absorption spectrometry, inductively coupled plasma mass spectrometry, flame photometry, gravimetric detection, chromatography, fluorometry,...

Published: 1/13/2023 | Inventor(s): Dipankar Koley, Partha Sheet

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Category(s): Biological Materials, Diagnostics

Two-row Facultative Multi-use Variety Named LIGHTNING™

Technology Description Lightning – this is the first facultative two-row multi-use variety in the world! It was developed by Oregon State University (OSU). The variety has excellent disease resistance, resistance to pre-harvest, sprouting, and will be a high yielding variety for those interested in producing barley for feed, pearling, and/or...

Published: 3/16/2024 | Inventor(s): Patrick Hayes, Tanya Filichkin, Scott Fisk, Laura Helgerson

Keywords(s): Agriculture, Malting

Category(s): Agricultural, Biological Materials

In-Situ Bioremediation with Slow Release Co-metabolism Substrates

Background of Invention A variety of highly toxic contaminants of concern persist in soils and groundwater at industrial sites across the country. Treatment, if even feasible, is often very expensive and time consuming. In-situ bioremediation of multiple contaminants with slow release cometabolism allows is attractive, but faces challenges of substrate...

Published: 8/3/2023 | Inventor(s): Mitchell Rasmussen, Lewis Semprini, Michael Hyman

Keywords(s): Bacteria, Bioremediation

Category(s): Biological Materials, Chemical, Engineering, Materials Science, Sustainability & Cleantechnologies

Synthetic Cephalotaxine Synthesis and New Anti-Cancer Compounds

Technology Description Oregon State University is seeking a licensee for an improved method to synthesize chemotherapeutic Homoharringtonine (HHT) that overcomes the need to use plant derived cephalotaxine. The synthetic method provides a high yield of chemically synthesized cephalotaxine as an HHT precursor and also enables the synthesis of novel...

Published: 1/13/2023 | Inventor(s): Chris Beaudry, Xuan Ju

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Category(s): Biological Materials, Chemical, Therapeutics

Two-row winter malting variety named THUNDER™

Technology Description THUNDER™ - a two-row winter, malting barley developed by Oregon State University (OSU) - has met AMBAs requirements and was selected for the 2019 recommendation list for malting barley’s. THUNDER™ is higher yielding than Endeavor and equivalent to Wintmalt, considering all the available data: irrigated, dryland,...

Published: 3/18/2024 | Inventor(s): Patrick Hayes, Chris Mundt, Tanya Filichkin, Scott Fisk, Laura Helgerson, Brigid Meints

Keywords(s): Agriculture, Barley, Malting, Plant, Plant Varieties

Category(s): Agricultural, Biological Materials

Mouse Model for Vitamin D Regulated Antimicrobial Peptide Expression

Technology Description Oregon State University is seeking collaborative research opportunities or licensees for a humanized mouse model for vitamin D regulated antimicrobial peptide expression. The developed animal model is a transgenic mouse that carries a 6.2 kb human genomic DNA that possess the cathelicidin antimicrobial peptide (CAMP) gene. Vitamin...

Published: 1/16/2023 | Inventor(s): Adrian Gombart

Keywords(s): Animal Model, Antimicrobial, Biotechnology, Vitamin D regulation

Category(s): Therapeutics, Biological Materials, Research Tools

Anti-cancer Compounds

Technology Description This technology describes using compounds to induce cell death in Bcl-2 high-expressing cancer cells refractory to chemotherapeutic drugs but with minimal effects on normal cells. Further, the anti-cancer effect of these compounds is also confirmed in mouse xenograft studies. These results indicate that our compounds are effective...

Published: 1/7/2022 | Inventor(s): Siva Kolluri, Prasad Kopparapu

Keywords(s): Cancer, metastatic tumor, small peptides

Category(s): Biological Materials, Chemical, Diagnostics, Research Tools, Therapeutics

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