Search Results - cancer

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Anti-cancer Compounds
Technology Description This technology describes using compounds to induce cell death in Bcl-2 high-expressing cancer cells refractory to chemotherapeutic drugs but with minimal effects on normal cells. Further, the anti-cancer effect of these compounds is also confirmed in mouse xenograft studies. These results indicate that our compounds are effe...
Published: 4/10/2017   |   Inventor(s): Siva Kolluri, Prasad Kopparapu
Keywords(s): Cancer, metastatic tumor, small peptides
Category(s): Biological Materials, Chemical, Diagnostics, Research Tools, Therapeutics
A Method to Treat Alzheimer’s, Heart and Liver Diseases
Technology Description This technology describes a process for the preparation of the tripeptide glutathione or its precursors to be delivered to the mitochondria for treating age-related conditions, toxicologic exposures, neurodegeneration, heart disease, and liver damage. More specifically, glutathione precursors and derivatives are coupled to a ...
Published: 3/28/2017   |   Inventor(s): Tory Hagen, Joseph Beckman, Pamela Beilby
Keywords(s): ALS, Alzheimer's, Antioxidant, Cancer, Liver disease, Medical Science & Technologies, Mitochondria, Neurodegenerative disease
Category(s): Biological Materials, Chemical, Diagnostics, Research Tools, Therapeutics
Pactamycin Analogs Having Antibacterial, Antitumor, and Antimalarial Activity
Technology Description: Patented (US8957251) pactamycin analogs having antibacterial, antitumor, antiviral and antimalarial activity. Also patented are biosynthetic methods of producing both the identified and additional new analogs. The identified analogs and methods of biosynthetic production provide a promising opportunity for discovery and deve...
Published: 5/17/2016   |   Inventor(s): Taifo Mahmud, Takuya Ito, Niran Roongsawang, Norifumi Shirasaka, Patricia Flatt
Keywords(s): Antibiotics, Antiviral, Cancer, Malaria
Category(s): Therapeutics
Drug delivery systems and formulations for treatment of metastatic melanoma (cancer)
Technology Description A nanocarrier drug delivery platform that provides a pharmaceutical composition configured for selective uptake by lymph nodes and dissemination throughout the lymphatic system such that administration of the composition provides therapeutic efficacy at lymph nodes both proximal and distal to the site of administration. A thr...
Published: 11/23/2015   |   Inventor(s): Adam (Wathah) Alani
Keywords(s): Cancer, Drug, Drug Delivery, drugs, Pharmaceuticals, Therapeutic
Category(s): Therapeutics
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