Search Results - biological materials

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Mouse Model for Vitamin D Regulated Antimicrobial Peptide Expression
Technology Description Oregon State University is seeking collaborative research opportunities or licensees for a humanized mouse model for vitamin D regulated antimicrobial peptide expression. The developed animal model is a transgenic mouse that carries a 6.2 kb human genomic DNA that possess the cathelicidin antimicrobial peptide (CAMP) gene. Vi...
Published: 7/6/2017   |   Inventor(s): Adrian Gombart
Keywords(s): Animal Model, Antimicrobial, Biotechnology, Vitamin D regulation
Category(s): Therapeutics, Biological Materials, Research Tools
Inducing Coordinated Sexual Reproduction in Diatoms
Technology Description This technology describes a simple and efficient way of inducing coordinated sexual reproduction in two strains of the centric diatom Thalassiosira pseudonana, and two other centric diatom species, Thalassiosira weissflogii and Cyclotella cryptica. This technology is likely applicable across all diatoms. Induction of the sexu...
Published: 6/7/2017   |   Inventor(s): Eric Moore, Kimberly Halsey
Keywords(s): algae, Ammonia, Biofuels, Biological & Environmental Engineering, Climate Change, diatom, Microbiology, Oceanography, reproduction, sex
Category(s): Agricultural, Biological Materials, Research Tools, Sustainability & Cleantechnologies, Therapeutics
Anti-cancer Compounds
Technology Description This technology describes using compounds to induce cell death in Bcl-2 high-expressing cancer cells refractory to chemotherapeutic drugs but with minimal effects on normal cells. Further, the anti-cancer effect of these compounds is also confirmed in mouse xenograft studies. These results indicate that our compounds are effe...
Published: 4/10/2017   |   Inventor(s): Siva Kolluri, Prasad Kopparapu
Keywords(s): Cancer, metastatic tumor, small peptides
Category(s): Biological Materials, Chemical, Diagnostics, Research Tools, Therapeutics
A Method to Treat Alzheimer’s, Heart and Liver Diseases
Technology Description This technology describes a process for the preparation of the tripeptide glutathione or its precursors to be delivered to the mitochondria for treating age-related conditions, toxicologic exposures, neurodegeneration, heart disease, and liver damage. More specifically, glutathione precursors and derivatives are coupled to a ...
Published: 3/28/2017   |   Inventor(s): Tory Hagen, Joseph Beckman, Pamela Beilby
Keywords(s): ALS, Alzheimer's, Antioxidant, Cancer, Liver disease, Medical Science & Technologies, Mitochondria, Neurodegenerative disease
Category(s): Biological Materials, Chemical, Diagnostics, Research Tools, Therapeutics
Mouse Model for Insulin Resistance
Opportunity Description Oregon State University is SEEKING RESEARCH COLLABORATIONS or LICENSEES for pharmaceutical R&D, or obesity and diabetes research, to exploit A NEW TYPE 2 DIABETES MOUSE MODEL. Created by Oregon State University professor Chrissa Kioussi, the mouse model is a SKELETAL MUSCLE SPECIFIC PITX2 NULL MOUSE. Development of the m...
Published: 2/22/2017   |   Inventor(s): Chrissa Kioussi
Keywords(s): Biotechnology, Diabetes, insulin resistance, Pharmaceuticals, Type 2 Diabetes
Category(s): Biological Materials, Chemical, Medical Devices, Therapeutics
Marine Probiotic
Technology Description A newly identified marine bacterium strain useful as an aquaculture probiotic. Preliminary inhibition assays demonstrate that full cell culture and cell-free culture supernatant of the probiotic are sufficient to inhibit growth of the following Vibrio species: V.coralliilyticus (oysters and corals), V.parahaemolyticus (seafoo...
Published: 12/27/2016   |   Inventor(s): Carla Schubiger
Keywords(s): aquaculture, coral, food-borne disease, oyster, probiotic, wound-infection
Category(s): Agricultural, Biological Materials, Therapeutics
Biological Oxidation of MTBE
Technology Description This invention utilizes the filamentous fungus Graphium sp., which is one of the few organisms known to grow on gaseous n-alkanes including; ethane, propane and n-butane. The fungus, while growing on n-alkanes, can cometabolically oxidize and degrade the gasoline oxygenate, methyl tert-butyl ether (MTBE). Methods for bioremed...
Published: 5/11/2016   |   Inventor(s): Michael Hyman, Lynda Ciuffetti
Keywords(s): Bacteria, Bio, Biofilter, Biofuels, Biological & Environmental Engineering, Biomechanics, Bioremediation, Cesium, Chemicals / Chemical Engineering, Environmental Remediation, Liquid-Liquid Extraction Process, Micro, Microbiology, Microorganism, natural product, Photochemical Catalytic Reactor, Phytochemical, Toxicology
Category(s): Agricultural, Biological Materials
Ultra-sensitive Surface-Enhanced Raman Scattering Substrates Patterned by Diatom Frustules
Background of Invention Surface-enhanced Raman spectroscopy (SERS) has been widely investigated as an analytical tool for detecting various biological and chemical molecules with single molecular sensitivity due to the strong electric fields induced by plasmonic resonances. Even though an enhancement factors as large as 1014 has been reported by co...
Published: 10/14/2014   |   Inventor(s): Alan Wang, Gregory Rorrer
Keywords(s): Biological & Environmental Engineering, Biotechnology, Materials Science
Category(s): Materials Science, Engineering, Device, Diagnostics, Nanoscience & Microtechnologies, Research Tools, Sustainability & Cleantechnologies, Biological Materials, Medical Devices, Physical Science, Therapeutics
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