Search Results - diagnostics

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Contact Lens with Transparent Biosensor Array
Technology Description This technology describes an array of field effect transistors (FETs) that are functionalized to detect biological markers with high sensitivity and specificity. The FET sensors are made of transparent materials processed at relatively low temperatures, allowing for the sensors to be deposited on clear and curved surfaces, su...
Published: 4/18/2017   |   Inventor(s): Gregory Herman
Keywords(s): Biomedical, biosensor, Diabetes, glucose sensor, health monitoring, Sensor-based monitoring, transparent electronics
Category(s): Device, Diagnostics, Engineering, Materials Science, Medical Devices, Nanoscience & Microtechnologies
Anti-cancer Compounds
Technology Description This technology describes using compounds to induce cell death in Bcl-2 high-expressing cancer cells refractory to chemotherapeutic drugs but with minimal effects on normal cells. Further, the anti-cancer effect of these compounds is also confirmed in mouse xenograft studies. These results indicate that our compounds are effe...
Published: 4/10/2017   |   Inventor(s): Siva Kolluri, Prasad Kopparapu
Keywords(s): Cancer, metastatic tumor, small peptides
Category(s): Biological Materials, Chemical, Diagnostics, Research Tools, Therapeutics
A Method to Treat Alzheimer’s, Heart and Liver Diseases
Technology Description This technology describes a process for the preparation of the tripeptide glutathione or its precursors to be delivered to the mitochondria for treating age-related conditions, toxicologic exposures, neurodegeneration, heart disease, and liver damage. More specifically, glutathione precursors and derivatives are coupled to a ...
Published: 3/28/2017   |   Inventor(s): Tory Hagen, Joseph Beckman, Pamela Beilby
Keywords(s): ALS, Alzheimer's, Antioxidant, Cancer, Liver disease, Medical Science & Technologies, Mitochondria, Neurodegenerative disease
Category(s): Biological Materials, Chemical, Diagnostics, Research Tools, Therapeutics
Low-Power Remote Logging Weight and Temperature Sensor
Technology Description The sensor includes a load cell, external temperature sensor, logger, and fuel container. The inexpensive monitor provides an easy launch via simple switch, data collection via SD card for ease of processing, a flexible power supply to last for any desired duration, and a cloud-based analysis platform to indicate the variabil...
Published: 2/15/2017   |   Inventor(s): Nordica MacCarty, Jennifer Ventrella
Keywords(s): biomass fuel sensor, Cookstoves, fuel efficiency algorithm, Household energy, Load cell logger, low power device, Sensor-based monitoring
Category(s): Device, Diagnostics, Engineering, Information Technology, Materials Science, Nanoscience & Microtechnologies, Physical Science, Research Tools, Software, Sustainability & Cleantechnologies
Fast, Economical, and Convenient Heavy Metal Contamination Detection
Technology Description This technology describes an accurate, inexpensive, simple, and portable membrane-based lateral flow fluidic device, made with both patented and patent pending technologies, to detect copper at concentrations as low as 0.5 ppm. No pre-treatment of the raw sample is needed. With simple modifications, this method can be adapted...
Published: 9/13/2016   |   Inventor(s): Gayan Bandara, Christopher Heist, Vincent Remcho
Keywords(s): Chemical Reaction Process, Diagnostic, Environmental Remediation, Manufacturing, Microchannel
Category(s): Device, Chemistry, Diagnostics, Nanoscience & Microtechnologies, Research Tools
Engineering Tumor Organoids for Cancer Drug Testing
Technology Description Diskoid In Geometrically Micropatterned Extracellular matrix (DIGME), is a 3D tissue patterning solution that controls the shape of cell organoids, as well as the surrounding ECM. Together, DIGME generates complex microenvironment niches closely mimicking physiological conditions to support and guide the invasion of tumor org...
Published: 9/7/2016   |   Inventor(s): Bo Sun, Amani Alobaidi
Keywords(s):  
Category(s): Diagnostics, Engineering, Therapeutics
Four Step Asymmetric Synthesis of the Anti-asthma Drug Singulair
Technology Description This technology is a simple and efficient way for synthesizing Singulair, a drug for the treatment of asthma and sesonal allergies.Features & Benefits Much more efficient and quicker synthesis pathway than that being used by big pharama (Merck)Applications Treatment for asthma and other allergic symptomsBackground of In...
Published: 7/20/2016   |   Inventor(s): James White, Subrata Shaw
Keywords(s):  
Category(s): Chemistry, Diagnostics, Research Tools
CTIP2 Diagnostic Marker for Head and Neck Cancer
Technology Description This technology opportunity provides a method for detecting CTIP2 or CTIP2L and for their use as biomarkers for squamous cell carcinoma. This technology can be used to develop kits for detecting SCC in a patient. The kit can include a CTIP2 and CTIP2L -specific antibody, oligonucleotides, or primers, and a chart or diagram s...
Published: 5/31/2016   |   Inventor(s): Arup Indra, Mark Leid, Joseph Abecassis, Gitali Indra
Keywords(s): Biomedical, Diagnostic, Pharmaceuticals, Research Tools
Category(s): Diagnostics
Apparatus and Method for Sensing Glucose Using Functionalized Amorphous In-Ga-Zn-O Field Effect Transistor
Technology Description This technology provides a method of continuous glucose sensing using nano-structured amorphous indium gallium oxide (IGZO) field effect transistors (FETs). IGZO-FETs can be processed at low temperatures that are compatible with flexible transparent substrates. A nano-structured IGZO has been applied to the surface of the FET...
Published: 5/23/2016   |   Inventor(s): Gregory Herman, Xiaosong Du
Keywords(s):  
Category(s): Diagnostics
Fluidic devices with photo-actuated gates and re-patternable channels
Technology Description This patented technology (US 8,580,161) describes ways of controlling fluid movement in microfluidic devices and microwell plates. Fluid movement is achieved by controlling gating, valving, and permeation using light-actuated compounds such as a spiropyran. Prototypes have been tested in the lab and we are looking for a lice...
Published: 5/20/2016   |   Inventor(s): Vincent Remcho, Jintana Nammoonnoy, Myra Koesdjojo
Keywords(s): Advanced Technology and Manufacturing Inst. (ATAMI), Biological & Environmental Engineering, Biomedical, Biotechnology, Chemicals / Chemical Engineering, Diagnostic, Medical Science & Technologies, Multiplexing, Nanotechnology, Physics / Applied Engineering, Research Tools
Category(s): Device, Chemical, Chemistry, Diagnostics, Engineering, Nanoscience & Microtechnologies, Research Tools
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