Paper-based Microfluidic Well Plates

Summary

Technology Description

 

This licensing opportunity relates to paper-based microfluidic analytical well plates and microfluidic well plates that provide a low cost alternative to conventional options. A means of fabricating multiple formats with polycaprolactone (PCL) has been developed, as well as a reusable frame and alignment device that allows the well plate to be used in currently available systems. Formats include paper-based well plates for UV-VIS or fluorescence detection, including low-volume and “dimple plate” formats. Additional formats include hybrid microfluidic well plates.

 

Features & Benefits

 

  • Low cost, simple, biodegradable, and disposable
  • High-throughput screening and analysis with minimal reagent handling
  • Compatible with a color chart for qualitative analysis or the user’s pre-existing laboratory plate reader for quantitative analysis of a panel of disease biomarkers, environmental and health toxins, and indicators of wellness.

 

Applications

 

  • Diagnostics
  • Chemical analysis
  • Environmental monitoring

 

Background of Invention

 

Microfluidic paper-based analytical devices (μPADS) have increased in popularity as a means of decreasing the cost of common clinical chemistry assays. There is currently no standard means of developing or modifying the assay chemistry, or detecting the resulting output (colorimetric or fluorescence). Similarly, there is a large segment of the developed world that can make use of a low-cost alternative to expensive well plates and manual processes for adding reagents commonly used for laboratory based assays.

 

Status

 

Patent pending

 

 

 

 

Patent Information:
Tech ID:
OSU-17-17
Contact:
Joe Christison
IP & Licensing Manager
Oregon State University
541-737-9016
joe.christison@oregonstate.edu
Inventors:
Christopher Heist
Sumate Pengpumkiat
Gayan Bandara
Vincent Remcho
Keywords:
Assay
Chemicals / Chemical Engineering
Detection
Diagnostic
Microfluidics
Paper
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