Search Results - Diagnostics

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Paper-based Microfluidic Well Plates
Technology Description This licensing opportunity relates to paper-based microfluidic analytical well plates and microfluidic well plates that provide a low cost alternative to conventional options. A means of fabricating multiple formats with polycaprolactone (PCL) has been developed, as well as a reusable frame and alignment device that allows th...
Published: 12/15/2017   |   Inventor(s): Christopher Heist, Sumate Pengpumkiat, Gayan Bandara, Vincent Remcho
Keywords(s): Assay, Chemicals / Chemical Engineering, Detection, Diagnostic, Microfluidics, Paper
Category(s): Research Tools, Diagnostics, Chemical, Nanoscience & Microtechnologies
Synthesis of Iridium Nanoparticles
Technology Description This technology licensing and collaborative research opportunity relates to simple aqueous synthetic methods that produce uncapped stable colloidal iridium nanoparticles (IrNPs). The synthesized IrNPs are highly crystalline as observed by X-ray diffraction and high resolution TEM imaging. In vitro metabolic toxicity assays us...
Published: 12/11/2017   |   Inventor(s): Conroy Sun, Anna Brown, Gaurav Sahay
Keywords(s): Iridium, Nanoparticles, Synthesis
Category(s): Chemical, Therapeutics, Physical Science, Diagnostics, Materials Science
Ultra-Sensitive Lab-on-Chip Sensor
Technology Description This technology is a lab-on-chip sensor incorporating aspects of both thin film chromatography and surface enhanced Raman spectroscopy as well as microchannel architecture to provide extremely high sensitivity detection of compounds in a mixed sample. A diatomite biosilica material functions as both the stationary phase for t...
Published: 9/27/2017   |   Inventor(s): Alan Wang, Xianming Kong, Kenneth Squire
Keywords(s): biosensor, Sensing, Surface enhanced Raman spectroscopy, Thin layer chromatography
Category(s): Device, Diagnostics, Engineering, Nanoscience & Microtechnologies
Contact Lens with Transparent Biosensor Array
Technology Description This technology describes an array of field effect transistors (FETs) that are functionalized to detect biological markers with high sensitivity and specificity. The FET sensors are made of transparent materials processed at relatively low temperatures, allowing for the sensors to be deposited on clear and curved surfaces, su...
Published: 4/18/2017   |   Inventor(s): Gregory Herman
Keywords(s): Biomedical, biosensor, Diabetes, glucose sensor, health monitoring, Sensor-based monitoring, transparent electronics
Category(s): Device, Diagnostics, Engineering, Materials Science, Medical Devices, Nanoscience & Microtechnologies
Anti-cancer Compounds
Technology Description This technology describes using compounds to induce cell death in Bcl-2 high-expressing cancer cells refractory to chemotherapeutic drugs but with minimal effects on normal cells. Further, the anti-cancer effect of these compounds is also confirmed in mouse xenograft studies. These results indicate that our compounds are effe...
Published: 4/10/2017   |   Inventor(s): Siva Kolluri, Prasad Kopparapu
Keywords(s): Cancer, metastatic tumor, small peptides
Category(s): Biological Materials, Chemical, Diagnostics, Research Tools, Therapeutics
A Method to Treat Alzheimer’s, Heart and Liver Diseases
Technology Description This technology describes a process for the preparation of the tripeptide glutathione or its precursors to be delivered to the mitochondria for treating age-related conditions, toxicologic exposures, neurodegeneration, heart disease, and liver damage. More specifically, glutathione precursors and derivatives are coupled to a ...
Published: 3/28/2017   |   Inventor(s): Tory Hagen, Joseph Beckman, Pamela Beilby
Keywords(s): ALS, Alzheimer's, Antioxidant, Cancer, Liver disease, Medical Science & Technologies, Mitochondria, Neurodegenerative disease
Category(s): Biological Materials, Chemical, Diagnostics, Research Tools, Therapeutics
Fast, Economical, and Convenient Heavy Metal Contamination Detection
Technology Description This technology describes an accurate, inexpensive, simple, and portable membrane-based lateral flow fluidic device, made with both patented and patent pending technologies, to detect copper at concentrations as low as 0.5 ppm. No pre-treatment of the raw sample is needed. With simple modifications, this method can be adapted...
Published: 9/13/2016   |   Inventor(s): Gayan Bandara, Christopher Heist, Vincent Remcho
Keywords(s): Chemical Reaction Process, Diagnostic, Environmental Remediation, Manufacturing, Microchannel
Category(s): Device, Chemistry, Diagnostics, Nanoscience & Microtechnologies, Research Tools
Engineering Tumor Organoids for Cancer Drug Testing
Technology Description Diskoid In Geometrically Micropatterned Extracellular matrix (DIGME), is a 3D tissue patterning solution that controls the shape of cell organoids, as well as the surrounding ECM. Together, DIGME generates complex microenvironment niches closely mimicking physiological conditions to support and guide the invasion of tumor org...
Published: 9/7/2016   |   Inventor(s): Bo Sun, Amani Alobaidi
Keywords(s):  
Category(s): Diagnostics, Engineering, Therapeutics
Four Step Asymmetric Synthesis of the Anti-asthma Drug Singulair
Technology Description This technology is a simple and efficient way for synthesizing Singulair, a drug for the treatment of asthma and sesonal allergies.Features & Benefits Much more efficient and quicker synthesis pathway than that being used by big pharama (Merck)Applications Treatment for asthma and other allergic symptomsBackground of In...
Published: 7/20/2016   |   Inventor(s): James White, Subrata Shaw
Keywords(s):  
Category(s): Chemistry, Diagnostics, Research Tools
CTIP2 Diagnostic Marker for Head and Neck Cancer
Technology Description This technology opportunity provides a method for detecting CTIP2 or CTIP2L and for their use as biomarkers for squamous cell carcinoma. This technology can be used to develop kits for detecting SCC in a patient. The kit can include a CTIP2 and CTIP2L -specific antibody, oligonucleotides, or primers, and a chart or diagram s...
Published: 5/31/2016   |   Inventor(s): Arup Indra, Mark Leid, Joseph Abecassis, Gitali Indra
Keywords(s): Biomedical, Diagnostic, Pharmaceuticals, Research Tools
Category(s): Diagnostics
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