Search Results - antibiotics

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Peptide Inhibitors of Gonorrhoeae
Technology Description Antigonococcal peptide inhibitors of Neisseria gonorrhoeae that act against a non-conventional new target, nitrite reductase AniA, that is necessary for N. gonorrhoeae anaerobic respiration and biofilm formation. The anaerobic life style is an important state during disease and favored in biofilms, which form in cervical gonococcal...
Published: 12/23/2021   |   Inventor(s): Aleksandra Sikora, Konstantin Korotkov
Keywords(s): Antibiotics, Antimicrobial, Drug, Drug Development, Gonorrhea, Inhibitor, Microbiology, Peptide, Therapeutic
Category(s): Therapeutics, Vaccines
Pactamycin Analogs Having Antibacterial, Antitumor, and Antimalarial Activity
Technology Description: Patented (US8957251) pactamycin analogs having antibacterial, antitumor, antiviral and antimalarial activity. Also patented are biosynthetic methods of producing both the identified and additional new analogs. The identified analogs and methods of biosynthetic production provide a promising opportunity for discovery and development...
Published: 1/7/2022   |   Inventor(s): Taifo Mahmud, Takuya Ito, Niran Roongsawang, Norifumi Shirasaka, Patricia Flatt
Keywords(s): Antibiotics, antiviral, Cancer, Malaria
Category(s): Therapeutics
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