Apoptolidin-producing Strain Amycolatopsis sp. ICBB 8242

Background
Apoptolidin is a macrolide. It was originally identified on the basis of its ability to selectively kill E1A and E1A/E1B19K transformed rat glial cells.

Technology Description
A bacterial strain that produces a family of antibiotic compounds known as the apoptolidins. The predominant compound produced is apoptolidin A.

• Benefits include Increased Yield compared to published strains
• Applications include antibiotic and anticancer lead compound development

Opportunity
Seeking a licensee, industry research sponsor, or collaborative research opportunity

Status
Available under a non-exclusive biological material license