This technology provides a new avenue for production of UV-protective gadusol, which can be used in novel, natural product-based sunscreens and cosmetic formulations. Production may be carried out in bacterial or yeast strains. In laboratory tests, gadusol produced by the engineered microbes displays UV-protective activity. The engineered microbes may be used for large-scale and environmentally friendly production of gadusol for commercial use.
Features & Benefits
Background of Invention
Health problems related to sun exposure are on the rise. Unfortunately, consumers’ choices in sunscreens remain limited, especially for formulations derived from naturally- occurring sun-protective compounds. One such compound, gadusol, is a promising UV-protective compound commonly found in marine fish. To address the need for new, natural sunscreen components, researchers at Oregon State University have developed a method for production of gadusol in genetically-engineered microbes.