Antiviral Agents Against Enveloped Viruses

Summary

Technology Description

This technology licensing opportunity is for patent pending methods for killing enveloped viruses, such as coronaviruses. It involves the application of known surfactants at concentrations much lower than were previously recognized as useful. Specifically, the compositions comprise highly purified surfactants at concentrations that, for external applications, should improve safety and reduce skin irritation, while also providing rapid killing of viruses. Current data demonstrates the compositions are useful against herpesviruses, however, the mechanism of killing should extend to any enveloped virus, including coronaviruses. Potential applications include antiviral disinfectants, sanitizers, nasal wash solutions, organ storage solutions, and medical device or personal protective equipment with antiviral properties. The technology is at an early stage. Oregon State University is seeking licensees interested in rapidly proving out the utility of the technology and bringing new products to market. It is available for licensing under our COVID-19 Initiative, which provides a free two-year license to qualified companies.

Features & Benefits

  • Anti-viral activity at concentrations that should be biologically safe for external applications
  • Rapid killing of enveloped viruses

Applications

  • Anti-viral surface disinfectants and sanitizers
  • Organ storage solutions
  • Anti-viral medical devices and personal protective equipment

Background of Invention

Enveloped viruses, such as coronaviruses, Influenza viruses, and herpesviruses, contain a phospholipid bilayer that is called the envelope. Surfactants, also called detergents, are amphiphilic organic compounds comprised of a hydrophobic non-polar hydrocarbon moiety (tail) and a hydrophilic polar head.

Status

U.S. patent pending; available for licensing

   

Bright light images of Vero cells with or without HSV-1 infection.
The concentration of surfactant is above the Vero cell image at 24h post-infection.
The bright light images were captured at 10X magnification.

Patent Information:
Tech ID:
OSU-20-34
Contact:
Joe Christison
IP & Licensing Manager
Oregon State University
541-737-9016
joe.christison@oregonstate.edu
Inventors:
Ling Jin
Keywords:
antiviral
corona
coronavirus
covid-19
envelop
viral
virus
© 2020. All Rights Reserved. Powered by Inteum