Search Results - mrna+delivery

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mRNA Therapeutic Against the SARS-CoV-2 Spike Protein

Background Vaccines have shown great efficacy against SARS-CoV-2, the pathogen of COVID-19; however, methods of treatment are required for patients suffering from COVID‑19. More than 15 million cases with over 600,000 deaths have resulted from the ongoing coronavirus disease 2019 (COVID-19). SARS-CoV-2, the pathogen of COVID-19, is a β-coronavirus...

Published: 8/4/2022 | Inventor(s): Gaurav Sahay, Anindit Mukherjee, Jeonghwan Kim

Keywords(s): antiviral, Drug, Drug Delivery, mRNA, mRNA carrier, mRNA delivery

Category(s): Therapeutics

Treatment for Muscle Atrophy and for Enhancing Muscle Growth

Technology Description This technology licensing and collaboration opportunity is for an mRNA based therapeutic that provides for increased hepatic production of follistatin (FS). In vivo experiments demonstrate delivered mRNA accumulates in the liver, which results in an increase of FS in blood serum. Mouse studies demonstrate a subcutaneous injection...

Published: 12/23/2021 | Inventor(s): Oleh Taratula, Canan Schumann, Olena Taratula, Adam Alani

Keywords(s): atrophy, growth, mRNA carrier, mRNA delivery, muscle, Muscular Dystrophy, wasting

Category(s): Therapeutics